In vitro T lymphocyte adherence capabilities under the influence of lower induction values (0.1-0.01 mT) of 50 Hz external magnetic fields

0436558 - ÚFE 2015 RIV GB eng C - Konferenční příspěvek (zahraniční konf.)
Čoček, A. - Jandová, Anna - Hahn, A. - Mártonová, J. - Ambruš, M. - Dohnalová, A. - Nedbalová, M. - Pokorný, Jiří
In vitro T lymphocyte adherence capabilities under the influence of lower induction values (0.1-0.01 mT) of 50 Hz external magnetic fields.
9TH INTERNATIONAL FROHLICH'S SYMPOSIUM: ELECTRODYNAMIC ACTIVITY OF LIVING CELLS (INCLUDING MICROTUBULE COHERENT MODES AND CANCER CELL PHYSICS). Vol. 329. Bristol: IOP, 2011 - (Cifra, M.; Pokorny, J.; Kučera, O.), 012031. ISSN 1742-6588.
[9th International Frohlich's Symposium on Electrodynamic Activity of Living Cells - Including Microtubule Coherent Modes and Cancer Cell Physics. Praha (CZ), 01.07.2011-03.07.2011]
Výzkumný záměr: CEZ:AV0Z20670512
Klíčová slova: Cancer patients * Control groups * External magnetic field
Kód oboru RIV: JA - Elektronika a optoelektronika, elektrotechnika

Our research thus far has concerned the impact of external magnetic fields (50 Hz) and low (0.01-10 mT) induction on adherence capabilities of T lymphocytes obtained from the blood of patients with head and neck tumors. We know that the in vitro adherence capability of T lymphocytes towards surfaces in cancer patients is less than that of control. Previously, we have found that exposure to magnetic fields (50 Hz / 0.01-10 mT) increases the capability of T lymphocytes, in larynx/pharynx cancer patients, to adhere in vitro to surfaces, achieving almost physiological values, in not only pre-treatment patients but also those receiving treatment in the course of follow-up. The capability of T lymphocytes in controls (voluntary blood donors) to adhere to surfaces was also increased (50 Hz / 0.01-0.5 mT). The present study concentrates on the significance of the level of magnetic field induction in order to determine whether low induction values can restore T lymphocytes adherence capabilities. Testing a set of 20 patients showed a statistically significant difference (p < 0.05) in the in vitro adherence capacity of T lymphocytes between both 0.01 and 0.05, and 0.1 mT induction levels. In the control group (patients diagnosed with chronic sensorineural hearing loss) there was even a statistically significant difference between induction values of 0.05 and 0.01 mT. Therefore, we concluded that lower induction values resulted in a more biologically significant response
Trvalý link: http://hdl.handle.net/11104/0240264