Počet záznamů: 1
The effect of dibenzo-p-dioxin- and dibenzofuran-contaminated soil on the earthworm Eisenia andrei
- 1.0435255 - MBÚ 2015 RIV GB eng J - Článek v odborném periodiku
Roubalová, Radka - Dvořák, Jiří - Procházková, Petra - Elhottová, Dana - Rossmann, Pavel - Škanta, František - Bilej, Martin
The effect of dibenzo-p-dioxin- and dibenzofuran-contaminated soil on the earthworm Eisenia andrei.
Environmental Pollution. Roč. 193, OCT 2014 (2014), s. 22-28. ISSN 0269-7491. E-ISSN 1873-6424
Grant CEP: GA MŠMT(CZ) EE2.3.20.0055; GA MŠMT(CZ) EE2.3.30.0003; GA MŠMT(CZ) ED1.1.00/02.0109
Institucionální podpora: RVO:61388971 ; RVO:60077344
Klíčová slova: Eisenia andrei * PCDD/Fs * Calreticulin
Kód oboru RIV: EE - Mikrobiologie, virologie
Impakt faktor: 4.143, rok: 2014
Polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) belong to the group of persistent organic pollutants, highly toxic environmental pollutants that include hydrophobic compounds with the tendency to bioaccumulate. Earthworms (Eisenia andrei) were exposed to PCDD/Fs-contaminated soil, and changes in their lipophilic structures and the gene expression of their defense molecules were followed. Damage to the intestinal wall and adjacent chloragogenous tissue was observed. Further, the up-regulation of the expression of several genes was detected. On the basis of these results, the mechanism of the impact of PCDD/Fs on earthworms has been proposed. Dioxins that accumulate in the lipophilic structures cause an increase in reactive oxidative species that triggers oxidative stress followed by the gene expression of two molecules that play a role in protection against oxidant toxicity, calreticulin (CRT) and Hsp70. Moreover, the effect of microbial biomass on the expression of coelomic cytolytic factor (CCF), a pattern recognition receptor, was also observed.
Trvalý link: http://hdl.handle.net/11104/0239202
Počet záznamů: 1