Getting it right before transplantation: example of a stem cell model with regenerative potential for the CNS

0435204 - ÚEM 2015 RIV CH eng J - Článek v odborném periodiku
Viero, C. - Forostyak, Oksana - Syková, Eva - Dayanithi, Govindan
Getting it right before transplantation: example of a stem cell model with regenerative potential for the CNS.
Frontiers in Cell and Developmental Biology. -, č. 2 (2014), s. 36. ISSN 2296-634X. E-ISSN 2296-634X
Grant CEP: GA ČR GAP304/11/2373; GA ČR(CZ) GAP304/11/0184; GA ČR(CZ) GBP304/12/G069; GA MŠMT EE2.3.20.0274
Institucionální podpora: RVO:68378041
Klíčová slova: human embryonic stem sell * neural precursors * neurodegenerative diseases
Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy

We gather results from our previous studies and present a cell model that was successfully used in functional analyses and engraftment experiments. These neuronal precursors exhibit spontaneous and evoked activity, indicating that their electrophysiological and calcium handling properties are similar to those of matured neurons. Hence this summarized information will serve as a basis to design better stem cell-based therapies to improve neural regeneration.
Trvalý link: http://hdl.handle.net/11104/0241902