Development of Composite Poly(Lactide-co-Glycolide)- Nanodiamond Scaffolds for Bone Cell Growth

0434298 - FGÚ 2016 RIV US eng J - Článek v odborném periodiku
Brady, M.A. - Renzing, A. - Douglas, T.E.L. - Liu, Q. - Wille, S. - Pařízek, Martin - Bačáková, Lucie - Kromka, Alexander - Jarošová, Markéta - Godier, G. - Warnke, P. H.
Development of Composite Poly(Lactide-co-Glycolide)- Nanodiamond Scaffolds for Bone Cell Growth.
Journal of Nanoscience and Nanotechnology. Roč. 15, č. 2 (2015), s. 1060-1069. ISSN 1533-4880
Grant CEP: GA ČR(CZ) GBP108/12/G108
Institucionální podpora: RVO:67985823 ; RVO:68378271
Klíčová slova: diamond nanoparticles * PLGA * human MSC * nanofibres * cytocompatibility * cell growth
Kód oboru RIV: JJ - Ostatní materiály
Impakt faktor: 1.338, rok: 2015

Using bionanotechnology we have successfully developed a PLGA-ND nanocomposite scaffold for cell growth. The basic physical fibre properties were established using SEM, TEM and AFM. Cytocompatibility and subsequent cell growth was established, paving the way for potential use of the composite PLGA-ND scaffolds in bone tissue engineering and also for bioactivation-specifically, as a drug delivery vehicle for a range of diseases. The future of the use of diamond in bionanotechnology holds out the potential of the development of multi-functional devices that target cells, deliver drugs and image reactions simultaneously
Trvalý link: http://hdl.handle.net/11104/0238402