Embryonic Toxicity of Nanoparticles

0433704 - ÚŽFG 2015 RIV CH eng J - Článek v odborném periodiku
Celá, Petra - Veselá, Barbora - Matalová, Eva - Večeřa, Zbyněk - Buchtová, Marcela
Embryonic Toxicity of Nanoparticles.
Cells Tissues Organs. Roč. 199, č. 1 (2014), s. 1-23. ISSN 1422-6405. E-ISSN 1422-6421
Grant CEP: GA ČR(CZ) GAP503/11/2315; GA ČR(CZ) GBP503/12/G147
Institucionální podpora: RVO:67985904 ; RVO:68081715
Klíčová slova: development * nanotechnology * toxicology * chicken * mouse
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 2.137, rok: 2014

Applications of nanoparticles (NP) in medicine, industry and other branches of human activities undoubtedly contribute to technology development and well-being. However, as NP are very small units in a wide range of materials, there is a lack of information related to possible side effects potentially affecting the health of organisms. There is increasing experimental interest in the determination of environmental effects on humans exposed to NP. Most such experimental studies focus on adult populations or adult experimental animals. However, embryos can be more sensitive to pollutants and environmental impacts in some species. Therefore, some investigations dealing particularly with the effects of NP on embryonic development have appeared recently and this issue is becoming of great concern. The aim of this review is to summarize the knowledge on the effects of various nanomaterials on embryonic development. A comprehensive collection of significant experimental nanotoxicity data is presented, which also indicate how the toxic effect of NP can be mediated and modulated with respect to possible effective protection strategies.
Trvalý link: http://hdl.handle.net/11104/0237902