Functionalized nanofibers as drug-delivery systems for osteochondral regeneration

0430262 - ÚEM 2015 RIV GB eng J - Článek v odborném periodiku
Amler, Evžen - Filová, Eva - Buzgo, Matej - Prosecká, Eva - Rampichová, Michala - Nečas, A. - Nooeaid, P. - Boccaccini, A. R.
Functionalized nanofibers as drug-delivery systems for osteochondral regeneration.
Nanomedicine. Roč. 9, č. 7 (2014), s. 1083-1094. ISSN 1743-5889. E-ISSN 1748-6963
Grant ostatní: GA MZd(CZ) NT12156; CEITEC CZ.1.05/1.1.00/02.0068; GA UK(CZ) 626012; GA UK(CZ) 384311; GA UK(CZ) 545313; GA UK(CZ) 424213; GA UK(CZ) 270513; GA MŠk(CZ) CZ.1.07/2.3.00/20.0092
Institucionální podpora: RVO:68378041
Klíčová slova: bone * cartilage * drug delivery
Kód oboru RIV: BO - Biofyzika
Impakt faktor: 5.413, rok: 2014

Nanofibers are very interesting carriers for drug delivery. This is because nanofibers are versatile, flexible, nanobiomimetic and similar to extracellular matrix components, possible to be functionalized both on their surface as well as in their core, and also because they can be produced easily and cost effectively. Nanofibers have also been favorably engaged as a drug-delivery system in cell-free scaffolds. This short overview is devoted to current applications and to further perspectives of nanofibers as drug-delivery devices in the field of cartilage and bone regeneration, and also in osteochondral reconstruction.
Trvalý link: http://hdl.handle.net/11104/0235775