Capillary electrophoresis applied to chiral analysis of helquats and characterization of their intermediates and interconversion barriers using randomly and single isomer sulfated cyclodextrins as stereoselectors

0430043 - ÚOCHB 2015 CZ eng C - Konferenční příspěvek (zahraniční konf.)
Kašička, Václav - Koval, Dušan - Sázelová, Petra - Severa, Lukáš - Vávra, Jan - Adriaenssens, Louis - Sonawane, Manoj R. - Teplý, Filip
Capillary electrophoresis applied to chiral analysis of helquats and characterization of their intermediates and interconversion barriers using randomly and single isomer sulfated cyclodextrins as stereoselectors.
Acta Universitatis Palackianae Olomucensis. Facultas Rerum Naturalium. Chemica 51S. Olomouc: Palacký University, 2014 - (Maier, V.; Ševčík, J.), s. 50-51. ISBN 978-80-244-3950-1. ISSN 0232-0061.
[Advances in Chromatography and Electrophoresis & Chiranal 2014. Olomouc (CZ), 10.02.2014-14.02.2014]
Grant CEP: GA ČR(CZ) GAP206/12/0453; GA ČR(CZ) GA13-17224S; GA ČR GA13-32974S
Institucionální podpora: RVO:61388963
Klíčová slova: helquats * chiral analysis * capillary electrophoresis
Kód oboru RIV: CB - Analytická chemie, separace

Capillary electrophoresis in acidic sodium phosphate background electrolyte, pH 2.4, with randomly sulfated alfa-, beta- and gamma-cyclodextrins as chiral selectors was applied to fast, high-resolution separation of enantiomers of a series of 35 helquats, a new class of N-heteroaromatic dicationic helicene-like species. The developed methodology was employed for evaluation of preparative enantioresolution procedures of helquats, for monitoring their racemization and for determination of interconversion barrier of helquat enantiomers.
Trvalý link: http://hdl.handle.net/11104/0235362