Trithiocyanurate Complexes of Iron, Manganese and Nickel and Their Anticholinesterase Activity

0429541 - ÚEB 2015 RIV CH eng J - Článek v odborném periodiku
Kopel, P. - Doležal, Karel - Langer, V. - Jun, D. - Adam, V. - Kuca, K. - Kizek, R.
Trithiocyanurate Complexes of Iron, Manganese and Nickel and Their Anticholinesterase Activity.
Molecules. Roč. 19, č. 4 (2014), s. 4338-4354. E-ISSN 1420-3049
Grant CEP: GA MŠMT(CZ) ED1.1.00/02.0068; GA MŠMT(CZ) LO1204
Institucionální podpora: RVO:61389030
Klíčová slova: crystal structure * trimercaptotriazine * trithiocyanuric acid
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 2.416, rok: 2014

The complexes of Fe(II), Mn(II) and Ni(II) with a combination of a Schiff base, nitrogen-donor ligand or macrocyclic ligand and trithiocyanuric acid (ttcH(3)) were prepared and characterized by elemental analysis and spectroscopies. Crystal and molecular structures of the iron complex of composition [Fe(L-1)](ttcH(2))(ClO4)center dot EtOH center dot H2O (1), where L-1 is Schiff base derived from tris(2-aminoethyl)amine and 2-pyridinecarboxaldehyde, were solved. It was found that the Schiff base is coordinated to the central iron atom by six nitrogens forming deformed octahedral arrangement, whereas trithiocyanurate(1-) anion, perchlorate and solvent molecules are not coordinated. The X-ray structure of the Schiff base sodium salt is also presented and compared with the iron complex. The anticholinesterase activity of the complexes was also studied.
Trvalý link: http://hdl.handle.net/11104/0234632