Biological half-life of xenobiotic bromide in the rat is dependent on sodium intake and varies with the metabolic activity of the animals

0425066 - FGÚ 2014 RIV SK eng C - Konferenční příspěvek (zahraniční konf.)
Pavelka, Stanislav
Biological half-life of xenobiotic bromide in the rat is dependent on sodium intake and varies with the metabolic activity of the animals.
Proceedings from 33rd International Symposium „Industrial Toxicology 2013“. Bratislava: Slovak University of Technology, 2013, s. 232-235. ISBN 978-80-227-3959-7.
[Industrial Toxicology 2013 /33./. Svit, Vysoké Tatry (SK), 19.06.2013-21.06.2013]
Institucionální podpora: RVO:67985823
Klíčová slova: bromide * sodium intake * biological half-life
Kód oboru RIV: FB - Endokrinologie, diabetologie, metabolizmus, výživa

The excretion rates of bromide were measured in animals situated in different physiological states. The shortest biological half-life of bromide/sodium ions (44 h) was determined in lactating dams and the longest (269 h) in breast-fed pups. The measured values demonstrate that lactating dams obviously waste sodium, due to their large food intake, whereas sucklings apparently conserve sodium, because of its relatively low concentration in breast milk
Trvalý link: http://hdl.handle.net/11104/0231009