Steroide anionic compounds, method of their production, usage and pharmaceutical preparation involving them

0423801 - ÚOCHB 2014 RIV eng P - Patentový dokument
Chodounská, Hana - Šťastná, Eva - Kapras, Vojtěch - Kohout, Ladislav - Borovská, Jiřina - Vyklický ml., Ladislav - Valeš, Karel - Cais, Ondřej - Rambousek, Lukáš - Stuchlík, Aleš - Valešová, V.
Steroide anionic compounds, method of their production, usage and pharmaceutical preparation involving them.
2013. Vlastník: Ústav organické chemie a biochemie AV ČR, v. v. i. - Fyziologický ústav AV ČR, v. v. i. - Psychiatrické centrum Praha. Datum udělení patentu: 05.11.2013. Číslo patentu: US8575376
Výzkumný záměr: CEZ:AV0Z40550506; CEZ:AV0Z50110509
Klíčová slova: steroide anionic compounds * central nervous system
Kód oboru RIV: CC - Organická chemie; ED - Fyziologie (FGU-C)
http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8575376.PN.&OS=PN/8575376&RS=PN/8575376

The invention deals with pregnanolone derivatives substituted in 3alpha-position with the anionic group bound in this position. These derivatives may be beneficial in treatment of several central nervous system (CNS) diseases, especially ischemic CNS injury, neurodegenerative alterations and diseases, post-traumatic stress disorder and other stress-related disorders, various psychotic diseases, pain, addiction, multiple sclerosis and autoimmune disorders, epilepsy, and CNS tumors.
Trvalý link: http://hdl.handle.net/11104/0229872