In vivo effect of focused shock waves on tumor tissue and its visualization by fluorescence staining techniques(BIOELECTRICS 2013 )

0422249 - ÚFP 2014 RIV DE eng O - Ostatní výsledky
Lukeš, Petr - Zeman, J. - Hoffer, Petr - Poučková, P. - Hosseini, S.H.R. - Akiyama, H. - Šunka, Pavel - Beneš, J.
In vivo effect of focused shock waves on tumor tissue and its visualization by fluorescence staining techniques(BIOELECTRICS 2013 ).
2013
Grant ostatní: Rada Programu interní podpory projektů mezinárodní spolupráce AV ČR(CZ) M100431203
Program: M
Institucionální podpora: RVO:61389021
Klíčová slova: shock waves * cancer * apoptosis * necrosis
Kód oboru RIV: BL - Fyzika plazmatu a výboje v plynech

Předneseno na:BIOELECTRICS 2013 – 10th International Bioelectrics Symposium,Karlsruhe,16.09.-19.09.2013, In this work we studied in vivo effects of focused tandem shock waves on the tumor tissue using TUNEL and DAPI fluorescence staining techniques. Lewis strain rats with syngeneic sarcoma transplanted into thighs were used as experimental animal model, tandem shock waves were generated by multichannel underwater discharge plasma. Necrotic and apoptotic changes induced by shock waves in tumor tissue were analyzed. The localization and the shape of tissue damage in form of a cone-shaped region correlated with the direction and the shape of shock wave propagation, which was determined in water using high speed shadowgraphy.
Trvalý link: http://hdl.handle.net/11104/0228452