Synthesis and Mass Spectral Fragmentation Patterns of Brassinolide Early Biosynthetic Precursors Labeled at C-26

0397254 - ÚEB 2014 RIV US eng J - Článek v odborném periodiku
Khripach, V.A. - Tarkowská, Danuše - Zhabinskii, V.N. - Gulyakevich, O.V. - Ermolovich, Y.V. - Drašar, P. - Strnad, M.
Synthesis and Mass Spectral Fragmentation Patterns of Brassinolide Early Biosynthetic Precursors Labeled at C-26.
Natural Product Communications. Roč. 8, č. 6 (2013), s. 771-774. ISSN 1934-578X. E-ISSN 1555-9475
Grant CEP: GA AV ČR IAA400550801
Grant ostatní: GA MŠk(CZ) ED0007/01/01
Program: ED
Výzkumný záměr: CEZ:AV0Z50380511
Klíčová slova: Brassinosteroids * Brassinolide * Biosynthesis
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 0.924, rok: 2013
http://www.naturalproduct.us/JournalArchive.asp

New analogues of brassinolide biosynthetic precursors with three deuterium atoms at non-exchangeable positions have been synthesized to be used as standards for quantification of natural brassinosteroids by liquid chromatography-mass spectrometry. [26-H-2(3)](22R,23R,24S)-22,23-Dihydroxy-6 beta-methoxy-24-methyl-3 alpha,5-cyclo-5 alpha-cholestane was used as a starting material for the preparation of campestane derivatives having a 22R,23R-diol functionality and either a hydroxy or keto group at C-3 and labeled at C-26. The mass spectrometric behavior of the newly synthesized compounds has been studied.
Trvalý link: http://hdl.handle.net/11104/0224899