The impact of lower induction values of 50 Hz external electromagnetic fields on in vitro T lymphocyte adherence capabilities

0396898 - ÚFE 2014 RIV US eng J - Článek v odborném periodiku
Čoček, A. - Hahn, A. - Mártonová, J. - Ambruš, M. - Dohnalová, A. - Nedbalová, M. - Jandová, Anna
The impact of lower induction values of 50 Hz external electromagnetic fields on in vitro T lymphocyte adherence capabilities.
Electromagnetic Biology and Medicine. Roč. 31, č. 2 (2012), s. 166-177. ISSN 1536-8378. E-ISSN 1536-8386
Institucionální podpora: RVO:67985882
Klíčová slova: Frohlich theory * Head and neck cancer * Electromagnetic field of power frequency
Kód oboru RIV: JA - Elektronika a optoelektronika, elektrotechnika
Impakt faktor: 0.814, rok: 2012

Our research thus far has concerned the impact of external electromagnetic fields (50 Hz) and low (0.0110 mT) induction on adherence capabilities of T lymphocytes obtained from the blood of patients with head and neck tumors. We know that the in vitro adherence capability of T lymphocytes towards surfaces in cancer patients is less than that of control. Previously, we have found that exposure to electromagnetic fields (50 Hz/0.0110 mT) increases the capability of T lymphocytes, in larynx/pharynx cancer patients, to adhere in vitro to surfaces, achieving almost physiological values, in not only pre-treatment patients but also those receiving treatment in the course of follow-up. The capability of T lymphocytes in controls (voluntary blood donors) to adhere to surfaces was also increased (50 Hz/0.010.5 mT).The present study concentrates on the significance of the level of electromagnetic field induction in order to determine whether low induction values can restore T lymphocytes adherence capabilities.Testing a subset of 20 patients showed a statistically significant difference (p < 0.05) in the in vitro adherence capacity of T lymphocytes between both 0.01 and 0.05, and 0.1 mT induction levels. In the control group (patients diagnosed with chronic sensorineural hearing loss) there was even a statistically significant difference between induction values of 0.05 and 0.01 mT. A statistically significant difference (p < 0.05) was also achieved with induction levels of 1 and 10 mT compared to 0.5, 0.1, and 0.05 mT, respectively. Therefore, we concluded that lower induction values resulted in a more biologically significant response
Trvalý link: http://hdl.handle.net/11104/0224622