Počet záznamů: 1
Derivatives of valproic acid are active against pentetrazol-induced seizures in immature rats
- 1.0395566 - FGÚ 2014 RIV NL eng J - Článek v odborném periodiku
Mareš, Pavel - Kubová, Hana - Hen, N. - Yagen, B. - Bialer, M.
Derivatives of valproic acid are active against pentetrazol-induced seizures in immature rats.
Epilepsy Research. Roč. 106, 1-2 (2013), s. 64-73. ISSN 0920-1211. E-ISSN 1872-6844
Grant CEP: GA ČR(CZ) GAP304/10/1274; GA ČR(CZ) GBP304/12/G069
Výzkumný záměr: CEZ:AV0Z50110509
Institucionální podpora: RVO:67985823
Klíčová slova: experimental seizures * anticonvulsant action * derivatives of valproic acid * immature rats
Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
Impakt faktor: 2.190, rok: 2013
The most common antiepileptic drug valproic acid has serious side effects (teratogenicity, hepatotoxicity). Its derivatives which are devoiod of these side effects were tested in immature rats and exhibited much stronger anticonvulsant action than the parent drug
Trvalý link: http://hdl.handle.net/11104/0223581
Počet záznamů: 1