Characterization of Electrochemical Behavior of Lecithin-Cholesterol Mixture in Formation of Model Phospholipid Membranes

0392970 - ÚFCH JH 2014 RIV CZ eng C - Konferenční příspěvek (zahraniční konf.)
Nováková, Kateřina - Navrátil, Tomáš - Šestáková, Ivana - Mareček, Vladimír - Chýlková, J.
Characterization of Electrochemical Behavior of Lecithin-Cholesterol Mixture in Formation of Model Phospholipid Membranes.
XXXIII. Moderní elektrochemické metody. Sborník přednášek. Ústí nad Labem: Best servis, 2013 - (Navrátil, T.; Fojta, M.; Pecková, K.), s. 128-131. ISBN 978-80-905221-1-4.
[Moderní elektrochemické metody /33./. Jetřichovice (CZ), 20.05.2013-24.05.2013]
Grant CEP: GA ČR(CZ) GAP208/12/1645
Institucionální podpora: RVO:61388955
Klíčová slova: Phosphatidylcholine * Cholesterol * Model phospholipid membrane
Kód oboru RIV: CG - Elektrochemie

Electrochemical behavior of lecithin-cholesterol mixture in the form of phospholipid membranes (PLMs) was studied in this contribution. Lecithin (phosphatidylcholine) and cholesterol were chosen for this research, because they are essential for living cells. Electrochemical behavior of this system was studied using an electrochemical cell developed in our laboratory and with applying electrochemical impedance spectroscopy (EIS). Different ratios between lecithin and cholesterol placed on different polycarbonate substrates were tested. The influence of time and of temperature on formation of PLMs in presence of cholesterol was investigated.
Trvalý link: http://hdl.handle.net/11104/0221728