Reciprocal regulation of A-to-I RNA editing and the vertebrate nervous system

0392529 - FGÚ 2014 RIV CH eng J - Článek v odborném periodiku
Penn, A.C. - Balík, Aleš - Greger, I. H.
Reciprocal regulation of A-to-I RNA editing and the vertebrate nervous system.
Frontiers in Neuroscience. Roč. 7, April (2013), s. 61. E-ISSN 1662-453X
Institucionální podpora: RVO:67985823
Klíčová slova: AMPA receptor * A-to-I RNA editing
Kód oboru RIV: ED - Fyziologie

The fine control of molecules mediating communication in the nervous system is key to adjusting neuronal signaling during development and in maitaining the stability of established networks. The nervous systems of metazoa have opted for expanding on post-transcriptional pre-mRNA splicing by altering key encoded amino acids using a conserved mechanism of A-to-I RNA editing. Here, we describe the recoding function of key RNA editing targets in the mammalian central nervous system and their potential to be regulated
Trvalý link: http://hdl.handle.net/11104/0221366