Folate Deficiency Is Associated With Oxidative Stress, Increased Blood Pressure, and Insulin Resistance in Spontaneously Hypertensive Rats

0392092 - FGÚ 2014 RIV US eng J - Článek v odborném periodiku
Pravenec, Michal - Kožich, V. - Krijt, J. - Sokolová, J. - Zídek, Václav - Landa, Vladimír - Šimáková, Miroslava - Mlejnek, Petr - Šilhavý, Jan - Oliyarnyk, O. - Kazdová, L. - Kurtz, T. W.
Folate Deficiency Is Associated With Oxidative Stress, Increased Blood Pressure, and Insulin Resistance in Spontaneously Hypertensive Rats.
American Journal of Hypertension. Roč. 26, č. 1 (2013), s. 135-140. ISSN 0895-7061. E-ISSN 1941-7225
Grant CEP: GA MZd(CZ) NS10036; GA MŠMT(CZ) ME10019; GA ČR(CZ) GAP303/10/0505; GA MŠMT(CZ) 7E10067
Institucionální podpora: RVO:67985823
Klíčová slova: blood pressure * ectopic fat accumulation * folate deficiency * homocysteine * hypertension * oxidative stress * spontaneously hypertensive rat
Kód oboru RIV: FB - Endokrinologie, diabetologie, metabolizmus, výživa
Impakt faktor: 3.402, rok: 2013

The SHR model is susceptible to the adverse metabolic and hemodynamic effects of low dietary intake of folate. The results are consistent with the hypothesis that folate deficiency can promote oxidative stress and multiple features of the metabolic syndrome that are associated with increased risk for diabetes and cardiovascular disease
Trvalý link: http://hdl.handle.net/11104/0221064