Počet záznamů: 1
Mapping genetic determinants of coronary microvascular remodeling in the spontaneously hypertensive rat
- 1.0392087 - FGÚ 2014 RIV DE eng J - Článek v odborném periodiku
Mancini, M. - Petretto, E. - Kleinert, C. - Scavone, A. - De, T. - Cook, S. - Šilhavý, Jan - Zídek, Václav - Pravenec, Michal - d´Amati, G. - Camici, P.G.
Mapping genetic determinants of coronary microvascular remodeling in the spontaneously hypertensive rat.
Basic Research in Cardiology. Roč. 108, č. 1 (2013), s. 316. ISSN 0300-8428. E-ISSN 1435-1803
Grant CEP: GA MŠMT(CZ) LH11049; GA MŠMT(CZ) LL1204; GA ČR(CZ) GAP301/12/0696
Institucionální podpora: RVO:67985823
Klíčová slova: arterial hypertension * coronary circulation * myocardial ischemia * spontaneously hypertensive rat * recombinant inbred strains
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 5.955, rok: 2013
To uncover possible genetic determinants of coronary microvascular remodeling, we carried out detailed histological and histomorphometric analysis of the heart and coronary vasculature in 30 weeks old SHR, age-matched Brown Norway (BN-Lx) parentals and BXH/HXB recombinant inbred (RI) strains. Using previously mapped expression quantitative trait loci (eQTLs), we carried out a genomewide association analysis and identified genetic determinants of cardiac gene expression and histomorphometric traits
Trvalý link: http://hdl.handle.net/11104/0221061
Počet záznamů: 1