Advances in Botanical Research

0390932 - BC 2013 RIV GB eng M - Část monografie knihy
Flegontov, Pavel - Lukeš, Julius
Mitochondrial genomes of photosynthetic euglenids and alveolates.
Advances in Botanical Research. Vol. 63. 24-28 OVAL ROAD, LONDON NW1 7DX: ACADEMIC PRESS LTD-ELSEVIER SCIENCE LTD, 2012 - (MarechalDrouard, L), s. 127-153. ISBN 978-0-12-394279-1
Grant CEP: GA ČR GA204/09/1667; GA ČR(CZ) GAP305/11/2179
Institucionální podpora: RVO:60077344
Klíčová slova: Dinoflagellate Alexandrium-Catenella * cytochrome-oxidase SUBUNIT-1 * transfer-RNA import * open reading frames * ribosomal-RNA * Plasmodium falciparum * messenger-RNAs * complete sequence * OXYRRHIS-MARINA * TETRAHYMENA-THERMOPHILA
Kód oboru RIV: EB - Genetika a molekulární biologie

Euglenida belong to the eukaryotic supergroup Excavata, the members of which possess the most varied mitochondrial genomes in terms of their structure and gene content. Heterotrophic protists represent the majority of Excavata, as only the Euglenida contain a green plastid, apparently acquired by secondary endosymbiosis. The sister group of Euglenida, the mostly parasitic Kinetoplastida, have an extremely complex mitochondrial DNA (kinetoplast DNA), which is usually composed of thousands of mutually interlocked DNA circles. Most mRNAs encoded by this genome are rendered translatable only after they undergo intricate editing via insertions and/or deletions of uridines. The mitochondrial DNA of the other sister group, Diplonemida, is unique as its transcripts must be massively trans-spliced before translation. None of these complex mechanisms has so far been found in the mitochondrial genome and transcriptome of Euglena gracilis, the best studied member of Euglenida. Its mitochondrial DNA exists in the form of numerous differently sized linear fragments. Their significant fraction is non-coding and full of various repeats, which intersperse fragments of a handful of protein-coding genes. Mostly photosynthetic dinoflagellates and parasitic apicomplexans with a relic plastid constitute a large and diverse group within alveolates. All species of this group share the most reduced mitochondrial genome found, containing just three, and in some cases probably two, protein-coding genes along with highly fragmented rRNA genes, and no tRNA genes. Mitochondrial genomes of dinoflagellates and those of smaller groups within the apicomplexa-dinoflagellata assemblage, perkinsids and chromerids, in all cases have a recombining, highly scrambled sequence, and frequently demonstrate other non-canonical features in structure and expression: fused genes, extensive RNA editing, trans-splicing, 5' oligoU caps, loss of start and stop codons, extensive translational frameshifting.
Trvalý link: http://hdl.handle.net/11104/0219802