Overcoming immunoescape mechanisms and induction of CD8(+) T cell-mediated resistance to tumor by polymer-bound doxorubicin conjugate targeted to tumor-specific antigen

0390550 - MBÚ 2013 GB eng A - Abstrakt
Kovář, Marek - Tomala, Jakub - Etrych, Tomáš - Ulbrich, Karel - Šírová, Milada - Říhová, Blanka
Overcoming immunoescape mechanisms and induction of CD8(+) T cell-mediated resistance to tumor by polymer-bound doxorubicin conjugate targeted to tumor-specific antigen.
Immunology 137. Glasgow: Blackwell Publishing Ltd, 2012. Roč. 137, č. 1 (2012), s. 719-719. ISSN 0019-2805. E-ISSN 1365-2567.
[European Congress of Immunology – ECI 2012. 05.09.2012-08.09.2012, Glasgow]
Grant CEP: GA ČR GAP301/11/0325; GA ČR GAP301/12/1254
Institucionální podpora: RVO:61388971 ; RVO:61389013
Klíčová slova: doxorubicin * HPMA copolymer * tumor
Kód oboru RIV: EC - Imunologie

This study was focused on interactions of immune system of the host with the tumor during and after the treatment course with doxorubicin bound to HPMA copolymer carrier and targeted with mAb to tumor-specific antigen
Trvalý link: http://hdl.handle.net/11104/0219427