Neuroglia

0388979 - ÚEM 2014 RIV US eng M - Část monografie knihy
Syková, Eva
Control of the extracellular ionic environment and volume.
Neuroglia. Vol. Third Edition. New York: Oxford University Press, 2013 - (Kettenmann, H. - Ransom, B. R.), s. 430-442. ISBN 978-0-19-979459-1
Grant CEP: GA ČR GA309/09/1597
Institucionální podpora: RVO:68378041
Klíčová slova: neurons * extracellular space * central nervous system
Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy

It is evident that glial cells play an important role in different brain functions. Voltage- and ligand-activated channels and a number of transport mechanisms on the glial membrane allow for the maintenance of ionic and volume homeostasis, which in turn affect neuronal function. The production of extracellular matrix molecules by activated astrocytes further hinders already impaired diffusion and contributes to an increase in tortuosity. Astrocytes can thus be viewed as active elements in signal transmission as they affect both synaptic as well as extrasynaptic volume transmission.
Trvalý link: http://hdl.handle.net/11104/0224759