Počet záznamů: 1
Mitochondrial Metabolism - Neglected Link of CancerTransformation and Treatment
- 1.0387401 - ÚFE 2013 RIV CZ eng J - Článek v odborném periodiku
Pokorný, Jiří - Jandová, Anna - Nedbalová, M. - Jelínek, František - Cifra, Michal - Kučera, Ondřej - Havelka, Daniel - Vrba, J. - Vrba, J. - Čoček, A. - Kobilková, J.
Mitochondrial Metabolism - Neglected Link of CancerTransformation and Treatment.
Prague Medical Report. Roč. 113, č. 2 (2012), s. 81-94. ISSN 1214-6994
Grant CEP: GA ČR(CZ) GAP102/11/0649
Institucionální podpora: RVO:67985882
Klíčová slova: Electromagnetic fields * Cellular biophysics * Cancer
Kód oboru RIV: JB - Senzory, čidla, měření a regulace
Mitochondria are at the boundary between chemical-genetic and physical processes of biological activity. Mitochondrial dysfunction in glycolytic cancer cells results in disturbed physical processes, very likely generated electromagnetic field, with consequent cell defective behavior-local invasion and metastasis. Cancer therapeutic strategy targeting mitochondria may restore physical functions of cells and open apoptotic pathway. Dichloroacetate treatment may lead to development of new anticancer drugs
Trvalý link: http://hdl.handle.net/11104/0216526
Počet záznamů: 1