Neuroscience - Dealing With Frontiers

0385863 - FGÚ 2013 RIV HR eng M - Část monografie knihy
Vávra, Vojtěch - Bhattacharya, Anirban - Jindřichová, Marie - Zemková, Hana
Facilitation of Neurotransmitter and Hormone Release by P2X Purinergic Receptors.
Neuroscience - Dealing With Frontiers. Rijeka: InTech, 2012 - (Contreras, C.), s. 61-82. ISBN 978-953-51-0207-6
Grant CEP: GA AV ČR(CZ) IAA500110910; GA ČR(CZ) GA305/07/0681; GA MŠMT(CZ) LC554; GA ČR(CZ) GPP304/12/P371
Výzkumný záměr: CEZ:AV0Z50110509
Institucionální podpora: RVO:67985823
Klíčová slova: ATP * purinergic P2X receptors * GABA * glutamate * pituitary * supraoptic nucleus * rat brain slices * patch clamp
Kód oboru RIV: ED - Fyziologie

Nucleotides are emerging as ubiquitous family of extracellular signaling molecules. Their effects are mediated through a specific class of plasma membrane receptors called purinergic P2 receptors that, according to the molecular structure, are further subdivided into two subfamilies: P2Y and P2X. This review summarizes recent investigations and our contribution to the knowledge about the molecular structure and mechanism of function of P2X receptors, and also how do they facilitate neurotransmitter release in the brain and secretion of hormones in pituitary
Trvalý link: http://hdl.handle.net/11104/0215073