Počet záznamů: 1
Differential distribution of glycine receptor subtypes at the rat calyx of Held synapse
- 1.0383851 - ÚEM 2013 RIV US eng J - Článek v odborném periodiku
Hrušková, Bohdana - Trojanová, Johana - Kulik, A. - Králíková, Michaela - Pysaněnko, Kateryna - Bureš, Zbyněk - Syka, Josef - Trussell, L. O. - Tureček, Rostislav
Differential distribution of glycine receptor subtypes at the rat calyx of Held synapse.
Journal of Neuroscience. Roč. 32, č. 47 (2012), s. 17012-17024. ISSN 0270-6474. E-ISSN 1529-2401
Grant CEP: GA ČR(CZ) GAP303/11/0131
Grant ostatní: Wellcome Trust(GB) WT073966
Výzkumný záměr: CEZ:AV0Z50390512
Institucionální podpora: RVO:68378041
Klíčová slova: glycine receptor * calyx of Held * auditory
Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
Impakt faktor: 6.908, rok: 2012
We show two functionally different glycine receptor populations in the rat medial nucleus of trapezoid body (MNTB). Postsynaptic receptors formed α1/β containing clusters on somatodendritic domains while presynaptic receptors were composed of dispersed, homomeric α1 receptors. The results suggest that specific targeting of glycine receptor β subunit produces segregation of glycine receptor subtypes involved in two different mechanisms of modulation of synaptic strength.
Trvalý link: http://hdl.handle.net/11104/0213664
Počet záznamů: 1