Počet záznamů: 1
Dynamics of caspase-3 activation and inhibition in embryonic micromasses evaluated by a photon-counting chemiluminiscence approach
- 1.0381779 - ÚIACH 2013 RIV US eng J - Článek v odborném periodiku
Chlastáková, Ivana - Lišková, Marcela - Kudělová, Judita - Dubská, L. - Klepárník, Karel - Matalová, Eva
Dynamics of caspase-3 activation and inhibition in embryonic micromasses evaluated by a photon-counting chemiluminiscence approach.
In Vitro - Cellular and Developmental Biology. Animal Section. Roč. 48, č. 9 (2012), s. 545-549. ISSN 1071-2690. E-ISSN 1543-706X
Grant CEP: GA ČR(CZ) GAP206/11/2377; GA MŠMT(CZ) EE2.3.20.0182
Grant ostatní: GA ČR(CZ) GAP502/12/1285
Program: GA
Výzkumný záměr: CEZ:AV0Z50450515; CEZ:AV0Z40310501
Klíčová slova: Caspases * apoptpsis * chemiluminiscence * camptothecin
Kód oboru RIV: CB - Analytická chemie, separace; ED - Fyziologie (UZFG-Y)
Impakt faktor: 1.289, rok: 2012
Caspases are key enzymatic components of the intracellular apoptotic machinery and their role in mammalian systems is often studied using fluoromethylketone (FMK) inhibitors. This work therefore focuses on an exact evaluation of caspase-3 FMK inhibition dynamics in camptothecin induced mesenchymal micromasses. A photon-counting chemiluminiscence approach was applied for quantification of active caspase-3.
Trvalý link: http://hdl.handle.net/11104/0212171
Počet záznamů: 1