Unprecedented Meta-Substitution of Calixarenes: Direct Way to Inherently Chiral Derivatives

0380824 - ÚOCHB 2013 RIV US eng J - Článek v odborném periodiku
Slavík, P. - Dudič, Miroslav - Flídrová, K. - Sýkora, Jan - Císařová, I. - Böhm, S. - Lhoták, P.
Unprecedented Meta-Substitution of Calixarenes: Direct Way to Inherently Chiral Derivatives.
Organic Letters. Roč. 14, č. 14 (2012), s. 3628-3631. ISSN 1523-7060. E-ISSN 1523-7052
Grant ostatní: GA ČR(CZ) GAP207/12/2027
Výzkumný záměr: CEZ:AV0Z40550506; CEZ:AV0Z40720504
Klíčová slova: uncommon regioselectivity * thiacalixarenes * nitration * formylation
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 6.142, rok: 2012

Electrophilic aromatic substitution in the calix[n]arene series is a well-established procedure leading exclusively to para-substituted derivatives. An unprecedented regioselectivity of the mercuration reaction leading to the meta-substituted calix[4]arenes is described. These compounds represent a new type of substitution pattern in classical calixarene chemistry and open the door for the straightforward synthesis of inherently chiral receptors based on calixarenes.
Trvalý link: http://hdl.handle.net/11104/0211436