Tumor promoting effects of cyanobacterial extracts are potentiated by anthropogenic contaminants – Evidence from in vitro study

0379736 - BÚ 2013 RIV GB eng J - Článek v odborném periodiku
Nováková, K. - Bláha, Luděk - Babica, Pavel
Tumor promoting effects of cyanobacterial extracts are potentiated by anthropogenic contaminants – Evidence from in vitro study.
Chemosphere. Roč. 89, č. 1 (2012), s. 30-37. ISSN 0045-6535. E-ISSN 1879-1298
Grant CEP: GA ČR GA524/08/0496
Grant ostatní: European Comission(XE) 2SGA2858-PS4CTX
Institucionální podpora: RVO:67985939
Klíčová slova: cyanobacteria * tumor promotion * gap junctional intercellular communication
Kód oboru RIV: EF - Botanika
Impakt faktor: 3.137, rok: 2012

Using rat liver epithelial cell line WB-F344 and assessment of gap junctional intercellular communication, it has been demonstrated that cyanobacterial extracts significantlly potentiated tumor promotional effects of common anthropogenic environmental contaminants, fluoranthene and polychlorinated biphenyl PCB153. This indicates possible synergistic pro-carcinogenic effects and interactions between different groups of environmental pollutants.
Trvalý link: http://hdl.handle.net/11104/0210621