Fate map of the dental mesenchyme: Dynamic development of the dental papilla and follicle

0379333 - ÚEM 2013 RIV US eng J - Článek v odborném periodiku
Rothová, Michaela - Peterková, Renata - Tucker, A. S.
Fate map of the dental mesenchyme: Dynamic development of the dental papilla and follicle.
Developmental Biology. Roč. 366, č. 2 (2012), s. 244-254. ISSN 0012-1606. E-ISSN 1095-564X
Grant CEP: GA ČR GA304/07/0223
Výzkumný záměr: CEZ:AV0Z50390703; CEZ:AV0Z50390512
Klíčová slova: tooth * mouse * mesenchyme
Kód oboru RIV: EA - Morfologické obory a cytologie
Impakt faktor: 3.868, rok: 2012

At the bud stage the mesenchymal cells adjacent to the tip of the bud form both the dental papilla and dental follicle. At the early cap stage a small population of highly proliferative mesenchymal cells in close proximity to the inner dental epithelium and primary enamel knot provide the major contribution to the dental papilla. These cells are located between the cervical loops, within a region we have called the body of the enamel organ, and proliferate in concert with the epithelium to create the dental papilla. The condensed dental mesenchymal cells that are not located between the body of the enamel organ, and therefore are at a distance from the primary enamel knot, contribute to the dental follicle, and also the apical part of the papilla, where the roots will ultimately develop. Some cells in the presumptive dental papilla at the cap stage contribute to the follicle at the bell stage, indicating that the dental papilla and dental follicle are still not defined populations at this stage.
Trvalý link: http://hdl.handle.net/11104/0210571