Počet záznamů: 1
Identification and interconversion of diastereomeric oligo-Troger bases probed by ion mobility mass spectrometry
- 1.0379208 - ÚOCHB 2013 RIV GB eng J - Článek v odborném periodiku
Révész, Agnes - Schröder, Detlef - Rokob, Tibor András - Havlík, M. - Dolenský, B.
Identification and interconversion of diastereomeric oligo-Troger bases probed by ion mobility mass spectrometry.
Physical Chemistry Chemical Physics. Roč. 14, č. 19 (2012), s. 6987-6995. ISSN 1463-9076. E-ISSN 1463-9084
Grant ostatní: GA ČR(CZ) GA203/08/1445; European Research Council(XE) AdG HORIZOMS
Výzkumný záměr: CEZ:AV0Z40550506
Klíčová slova: cross section * epimerization * ion mobility * mass spectrometry * Troeger bases
Kód oboru RIV: CF - Fyzikální chemie a teoretická chemie
Impakt faktor: 3.829, rok: 2012
Oligo-Troger bases are auspicious scaffolds of molecular engineering, which motivates studies on the mechanism of their interconversion and on the facile determination of the relative configuration of their diastereoisomers. Protonated, sodiated, and argentated species of those compounds were therefore studied via ion-mobility mass spectrometry (IM-MS), allowing differentiation on the basis of the shapes of the ions. First, the isomerization was confirmed to be acid-catalyzed as it takes place readily in the case of protonated Troger bases, whereas the metallated bases are configurationally stable. Second, the corrected arrival times of the various isomers of the cationized bases were found to show distinct differences in IM-MS, and their excellent correlation with the cross sections obtained from quantum chemical calculations paves the way toward the easy identification of diastereoisomers.
Trvalý link: http://hdl.handle.net/11104/0210468
Počet záznamů: 1