Počet záznamů: 1
An efficient microwave-assisted synthesis and biological properties of polysubstituted pyrimidinyl- and 1,3,5-triazinylphosphonic acids
- 1.0377689 - ÚOCHB 2013 RIV GB eng J - Článek v odborném periodiku
Jansa, Petr - Hradil, Ondřej - Baszczyňski, Ondřej - Dračínský, Martin - Klepetářová, Blanka - Holý, Antonín - Balzarini, J. - Janeba, Zlatko
An efficient microwave-assisted synthesis and biological properties of polysubstituted pyrimidinyl- and 1,3,5-triazinylphosphonic acids.
Tetrahedron. Roč. 68, č. 3 (2012), s. 865-871. ISSN 0040-4020. E-ISSN 1464-5416
Grant CEP: GA AV ČR KJB400550903; GA MŠMT 1M0508
Grant ostatní: K.U. Leuven(BE) GOA 10/014
Výzkumný záměr: CEZ:AV0Z40550506
Klíčová slova: phosphonic acids * pyrimidines * 1,3,5-triazines * microwave-assisted synthesis * influenza virus
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 2.803, rok: 2012
Polysubstituted pyrimidinylphosphonic and 1,3,5-triazinylphosphonic acids with potential biological properties were prepared in high yields by the microwave-assisted Michaelis-Arbuzov reaction of trialkyl phosphite with the corresponding halopyrimidines and halo-1,3,5-triazines, respectively, followed by the standard deprotection of the phosphonate group using TMSBr in acetonitrile.
Trvalý link: http://hdl.handle.net/11104/0209784
Počet záznamů: 1