A widespread occurrence of extra open reading frames in plant Ty3/gypsy retrotransposons

0377346 - BC 2013 RIV NL eng J - Článek v odborném periodiku
Steinbauerová, Veronika - Neumann, Pavel - Novák, Petr - Macas, Jiří
A widespread occurrence of extra open reading frames in plant Ty3/gypsy retrotransposons.
Genetica. Roč. 139, 11-12 (2011), s. 1543-1555. ISSN 0016-6707. E-ISSN 1573-6857
Výzkumný záměr: CEZ:AV0Z50510513
Klíčová slova: Additional ORFs * LTR retrotransposons * Repetitive DNA * Plant genome
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 2.148, rok: 2011

Long terminal repeat (LTR) retrotransposons make up substantial parts of most higher plant genomes where they accumulate due to their replicative mode of transposition. Although the transposition is facilitated by proteins encoded within the gag-pol region which is common to all autonomous elements, some LTR retrotransposons were found to potentially carry an additional protein coding capacity represented by extra open reading frames located upstream or downstream of gag-pol. In this study, we performed a comprehensive in silico survey and comparative analysis of these extra open reading frames (ORFs) in the group of Ty3/gypsy LTR retrotransposons as the first step towards our understanding of their origin and function. We found that extra ORFs occur in all three major lineages of plant Ty3/gypsy elements, being the most frequent in the Tat lineage where most (77 %) of identified elements contained extra ORFs. This lineage was also characterized by the highest diversity of extra ORF arrangement (position and orientation) within the elements.
Trvalý link: http://hdl.handle.net/11104/0209523