Herpesviridae - A Look Into This Unique Family of Viruses

0376660 - ÚOCHB 2013 RIV HR eng M - Část monografie knihy
Krečmerová, Marcela
Nucleoside and Nucleotide Analogues for the Treatment of Herpesvirus Infections: Current Stage and New Prospects in the Field of Acyclic Nucleoside Phosphonates.
Herpesviridae - A Look Into This Unique Family of Viruses. Rijeka: InTech, 2012 - (Magel, G.; Tyring, S.), s. 245-270. ISBN 978-953-51-0186-4
Grant CEP: GA MŠMT 1M0508
Výzkumný záměr: CEZ:AV0Z40550506
Klíčová slova: acyclic nucleoside phosphonates * acyclic nucleoside analogue * antimetabolite * DHPA * 5-azacytosine * cidofovir * HPMPDAP * prodrugs * animal herpesviruses
Kód oboru RIV: CC - Organická chemie
http://www.intechopen.com/books/herpesviridae-a-look-into-this-unique-family-of-viruses/nucleoside-and-nucleotide-analogues-for-the-treatment-of-herpesvirus-infections-current-stage-and-ne

Discovery of nucleic acid antimetabolites including DHPA and acyclic nucleoside phosphonates is described with respect to their clinical potential as anti-herpesvirus agents. New prospects in the treatment of herpesvirus related diseases bound to discovery HPMP-5-azaC and its prodrugs is discussed in detail, as well as clinical potential of HPMPDAP esters against poxviruses or possible utilization of ANP in veterinary medicine for the treatment of animal herpesvirus infections.
Trvalý link: http://hdl.handle.net/11104/0209006