Controlled/living surface-initiated ATRP of antifouling polymer brushes from gold in PBS and blood sera as a model study for polymer modifications in complex biological media

0376434 - ÚMCH 2013 RIV DE eng J - Článek v odborném periodiku
Rodriguez-Emmenegger, Cesar - Hasan, E. - Pop-Georgievski, Ognen - Houska, Milan - Brynda, Eduard - Bologna Alles, A.
Controlled/living surface-initiated ATRP of antifouling polymer brushes from gold in PBS and blood sera as a model study for polymer modifications in complex biological media.
Macromolecular Bioscience. Roč. 12, č. 4 (2012), s. 525-532. ISSN 1616-5187. E-ISSN 1616-5195
Grant CEP: GA AV ČR KAN200670701; GA ČR GAP503/10/0664
Výzkumný záměr: CEZ:AV0Z40500505
Klíčová slova: antifouling surfaces * atom-transfer radical polymerization (ATRP) * biocompatibility
Kód oboru RIV: EE - Mikrobiologie, virologie
Impakt faktor: 3.742, rok: 2012

The use of PBS, 10% FBS or 10% CS as media for SI-ATRP is reported. Controlled/living SI-ATRP of MeOEGMA in PBS is achieved leading to better control than in water. The livingness is confirmed by chain extension with MeOEGMA or carboxybetaine acrylamide. This technique is successfully adopted for the polymerization of MeOEGMA in 10% FBS or CS as models for complex biological media with reasonable control of the brush growth. All prepared brushes show excellent antifouling properties.
Trvalý link: http://hdl.handle.net/11104/0006959