Association Between TAS2R38 Gene Polymorphisms and Colorectal Cancer Risk: A Case-Control Study in Two Independent Populations of Caucasian Origin

0375559 - ÚEM 2012 RIV US eng J - Článek v odborném periodiku
Carrai, M. - Steinke, V. - Vodička, Pavel - Pardini, Barbara - Rahner, N. - Holinski-Feder, E. - Morak, M. - Schackert, H. K. - Görgens, H. - Stemmler, S. - Betz, B. - Kloor, M. - Engel, C. - Büttner, R. - Naccarati, Alessio - Vodičková, Ludmila - Novotný, J. - Stein, A. - Hemminki, K. - Propping, P. - Försti, A. - Canzian, F. - Barale, R. - Campa, D.
Association Between TAS2R38 Gene Polymorphisms and Colorectal Cancer Risk: A Case-Control Study in Two Independent Populations of Caucasian Origin.
PLoS ONE. Roč. 6, č. 6 (2011), e20464. ISSN 1932-6203. E-ISSN 1932-6203
Grant CEP: GA ČR GA310/07/1430; GA MŠMT 7F10069
Výzkumný záměr: CEZ:AV0Z50390512
Klíčová slova: CRC * bitter taste receptors
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 4.092, rok: 2011

Taste receptors over the whole gastrointestinal tract can influence the selection and intake of the food. In the present study we investigated all the common genetic variation of one taste receptor gene in relation to colorectal cancer risk. In conclusion, we found a suggestive association between the human bitter tasting phenotype and the risk of CRC in two different populations of Caucasian origin.
Trvalý link: http://hdl.handle.net/11104/0208178