Počet záznamů: 1
Appearance of alarmin HMGB1 in small intestine and plasma of gnotobiotic piglets infected with enteric pathogens
- 1.0375210 - MBÚ 2012 RIV CZ eng A - Abstrakt
Šplíchal, Igor - Šplíchalová, Alla - Chmelařová, Petra - Trebichavský, Ilja
Appearance of alarmin HMGB1 in small intestine and plasma of gnotobiotic piglets infected with enteric pathogens.
Sborník přednášek VI. sympozia Společnosti pro probiotika a prebiotika. Praha: ČZU Praha, 2011. s. 19-19. ISBN 978-80-213-2173-1.
[Sympozium Společnosti pro probiotika a prebiotika /6./. 19.04.2011, Praha]
Grant CEP: GA MŠMT ME 915; GA ČR GA523/07/0572
Výzkumný záměr: CEZ:AV0Z50200510
Klíčová slova: S. Typhimurium * E. coli
Kód oboru RIV: EC - Imunologie
One week old gnotobiotic piglets were orally infected with enteric bacterial pathogens S. Typhimurium or E. coli O55. High levels of HMGB1 in intestine and plasma of infected piglets 24 hours after infection correlated with clinical state of piglets (lethargy, anorexia, diarrhea) and severity of infection. Piglets colonized with probiotic E. coli Nissle 1917 kept the values comparable with germ-free controls
Trvalý link: http://hdl.handle.net/11104/0207933
Počet záznamů: 1