High-resolution biosensor based on localized surface plasmons

0374560 - ÚFE 2013 RIV US eng J - Článek v odborném periodiku
Piliarik, Marek - Šípová, Hana - Kvasnička, Pavel - Galler, N. - Krenn, J. R. - Homola, Jiří
High-resolution biosensor based on localized surface plasmons.
Optics Express. Roč. 20, č. 1 (2012), s. 672-680. ISSN 1094-4087
Grant CEP: GA AV ČR KAN200670701; GA MŠMT OC09058
Výzkumný záměr: CEZ:AV0Z20670512
Klíčová slova: optical biosenzor * surface plasmon resonance * localized surface plasmon
Kód oboru RIV: JA - Elektronika a optoelektronika, elektrotechnika
Impakt faktor: 3.546, rok: 2012

We report on a new biosensor with localized surface plasmons (LSP) based on an array of gold nanorods and TIR imaging in polarization contrast. The sensitivity of the new biosensor is characterized and a model detection of DNA hybridization is carried out and results compared with a conventional SPR biosensor, showing the same performance while involving significantly lower surface densities of interacting molecules. Limit of detection was 100 pM and a surface density resolution only 35 fg×mm2.
Trvalý link: http://hdl.handle.net/11104/0216253