Method of preparation of superparamagnetic nanoparticles based on iron oxides with modified surface and superparamagnetic nanoparticles obtained by such a method

0372221 - ÚMCH 2012 RIV DE eng P - Patentový dokument
Horák, Daniel - Syková, Eva - Babič, Michal - Jendelová, Pavla - Hájek, Milan
Method of preparation of superparamagnetic nanoparticles based on iron oxides with modified surface and superparamagnetic nanoparticles obtained by such a method.
Munich: European Patent Office, 2010. Vlastník: Ústav makromolekulární chemie AV ČR, v. v. i. - Ústav experimentální medicíny AV ČR, v. v. i. Datum udělení patentu: 08.09.2010. Číslo patentu: EP1991503
Grant CEP: GA MŠMT 1M0538
Klíčová slova: superparamagnetic * iron oxide * cell labeling
Kód oboru RIV: CD - Makromolekulární chemie
http://v3.espacenet.com/publicationDetails/originalDocument?CC=EP&NR=1991503B1&KC=B1&FT=D&date=20100908&DB=EPODOC&locale=en_EP

Superparamagnetic nanoparticles (~ 10 nm) were developed based on iron oxides. Their surface was modified with mono-, di- or polysaccharides, amino acids or poly(amino acid)s or synthetic polymers based on (meth)acrylic acid and their derivatives. Nanoparticles are suitable for diagnostic and therapeutical applications including labeling of living cells. The invention provides a tool for monitoring the history and fate of cells transplanted into organism including their in vivo migration.
Trvalý link: http://hdl.handle.net/11104/0205589