Gene and Cardivascular Function

0371679 - FGÚ 2012 RIV US eng M - Část monografie knihy
Kuneš, Jaroslav - Kadlecová, Michaela - Zicha, Josef
Gene-Environment Interactions: Their Role in Hypertension Development.
Gene and Cardivascular Function. New York: Springer, 2011 - (Ošťádal, B.; Nagano, M.; Dhalla, N.), s. 177-184. ISBN 978-1-4419-7206-4
Grant CEP: GA MŠMT(CZ) 1M0510; GA ČR(CZ) GA305/09/0336; GA AV ČR(CZ) IAA500110902
Výzkumný záměr: CEZ:AV0Z50110509
Klíčová slova: critical developmental periods * dietary interventions * epigenetics
Kód oboru RIV: ED - Fyziologie

The interactions of multiple genetic and environmental factors as well as gene-gene interactions cause modifications of various systems that adjust blood pressure to actual living conditions. Numerous environmental factors could modify the development of organism not only by the influence on the expression of genetic information but mainly by epigenetic influence It is difficult to identify all genetic determinants leading to hypertension and other cardiovascular diseases because they become a medical problem in adulthood, although their roots might be traced back to earlier stage sof ontogeny. The link between distinct developmental periods involves the changes in genetic expression including epigenetic phenomena
Trvalý link: http://hdl.handle.net/11104/0205149