Flavivirus Encephalitis

0370865 - BC 2012 RIV HR eng M - Část monografie knihy
Donoso-Mantke, O. - Karan, L. S. - Růžek, Daniel
Tick-Borne Encephalitis Virus: A General Overview.
Flavivirus Encephalitis. Rijeka: InTech, 2011 - (Růžek D.), s. 133-156. ISBN 978-953-307-669-0
Grant CEP: GA ČR GPP302/10/P438; GA ČR GAP502/11/2116; GA MŠMT(CZ) LC06009
Výzkumný záměr: CEZ:AV0Z60220518
Klíčová slova: Tick-borne encephalitis * European subtype * Siberian subtype * Far Eastern subtype * ixodid ticks
Kód oboru RIV: EB - Genetika a molekulární biologie

Tick-borne encephalitis (TBE) virus is classified as one species with three subtypes, namely the European subtype, the Siberian subtype and the Far Eastern subtype. TBE is distributed in an endemic pattern of so-called natural foci over a wide geographical areas. It is the most important flavivirus infection of the CNS in Europe and Russia, with about 13,000 estimated human cases per year. The epidemiology of TBE is closely related to the ecology and biology of ixodid ticks. In nature, TBE virus is propagated in a cycle involving permanently infected ticks and wild vertebrate hosts. Currently, the diagnosis of TBE is mainly based on the detection of specific antibodies in serum and cerebrospinal fluid. No specific treatment for the disease is available to date, but it can be prevented by active immunization. This chapter reviews all aspects related to TBE and provides basic information for clinicians, virologists, immunologists, as well as for students of medicine or life sciences.
Trvalý link: http://hdl.handle.net/11104/0204545