Redox labels and indicators based on transition metals and organic electroactive moieties for electrochemical nucleic acids sensing

0370535 - BFÚ 2012 RIV GB eng J - Článek v odborném periodiku
Fojta, Miroslav - Havran, Luděk - Pivoňková, Hana - Horáková Brázdilová, Petra - Hocek, Michal
Redox labels and indicators based on transition metals and organic electroactive moieties for electrochemical nucleic acids sensing.
Current Organic Chemistry. Roč. 15, č. 17 (2011), s. 2936-2949. ISSN 1385-2728. E-ISSN 1875-5348
Grant CEP: GA MŠMT(CZ) LC06035; GA MŠMT(CZ) LC512; GA AV ČR(CZ) IAA400040901; GA AV ČR(CZ) IAA400040903
Výzkumný záměr: CEZ:AV0Z50040507; CEZ:AV0Z50040702; CEZ:AV0Z40550506
Klíčová slova: electrochemical methods * modified DNA * biosensor
Kód oboru RIV: BO - Biofyzika
Impakt faktor: 3.064, rok: 2011

Electroactive indicators and labels are used in electrochemical nucleic acids sensing to improve selectivity and sensitivity of the biosensors and bioassays and to expand the palette of applicable electrode materials. Besides classical synthesis of modified nucleic acids, more facile and verstaile approaches have been introduced, based on either chemical modification of natural DNA components, or enzymatic incorporation of modified nucleotides.
Trvalý link: http://hdl.handle.net/11104/0204320