Počet záznamů: 1
Subtype Differences in Pre-Coupling of Muscarinic Acetylcholine Receptors
- 1.0370409 - FGÚ 2012 RIV US eng J - Článek v odborném periodiku
Jakubík, Jan - Janíčková, Helena - Randáková, Alena - El-Fakahany, E. E. - Doležal, Vladimír
Subtype Differences in Pre-Coupling of Muscarinic Acetylcholine Receptors.
PLoS ONE. Roč. 6, č. 11 (2011), e27732. ISSN 1932-6203. E-ISSN 1932-6203
Grant CEP: GA ČR(CZ) GA305/09/0681; GA AV ČR(CZ) IAA500110703; GA MŠMT(CZ) LC554
Výzkumný záměr: CEZ:AV0Z50110509
Klíčová slova: acetylcholine muscarinic receptors * G proteins * subtype differences
Kód oboru RIV: ED - Fyziologie
Impakt faktor: 4.092, rok: 2011
Data show that all subtypes of muscarinic receptors pre-couple with their preferential classes of G-proteins. M1 and M3 receptors also pre-couple with non-preferential Gi/o G-proteins. Pre-coupling is not dependent on agonist efficacy nor on receptor activation
Trvalý link: http://hdl.handle.net/11104/0204222
Počet záznamů: 1