Počet záznamů: 1
Structural Basis for the 14-3-3 Protein-dependent Inhibition of the Regulator of G Protein Signaling 3 (RGS3) Function
- 1.0370392 - FGÚ 2012 RIV US eng J - Článek v odborném periodiku
Řežábková, L. - Man, Petr - Novák, Petr - Herman, P. - Večeř, J. - Obšilová, Veronika - Obšil, T.
Structural Basis for the 14-3-3 Protein-dependent Inhibition of the Regulator of G Protein Signaling 3 (RGS3) Function.
Journal of Biological Chemistry. Roč. 286, č. 50 (2011), s. 43527-43536. ISSN 0021-9258. E-ISSN 1083-351X
Grant CEP: GA AV ČR(CZ) IAA501110801; GA ČR GAP207/10/1040; GA MŠMT(CZ) LC554
Grant ostatní: GA ČR(CZ) GAP305/11/0708; Univerzita Karlova(CZ) 28510
Výzkumný záměr: CEZ:AV0Z50110509; CEZ:AV0Z50200510
Klíčová slova: RGS3 * 14-3-3 * inhibition * signaling * SAXS * fluorescence
Kód oboru RIV: BO - Biofyzika
Impakt faktor: 4.773, rok: 2011
Background: The 14-3-3 protein binds to and regulates the function of the regulator of G protein signaling 3 (RGS3). Results: The 14-3-3 binding affects the structure of the G.alpha. interaction portion of RGS3. Conclusion: The 14-3-3 protein blocks the interaction between the RGS3 and the G.alpha.. Significance: This might explain the inhibitory function of 14-3-3 in the regulation of RGS3
Trvalý link: http://hdl.handle.net/11104/0204214
Počet záznamů: 1