Počet záznamů: 1
Tail labelled oligonucleotide probes for the detection of DNA-protein interactions
- 1.0361622 - ÚOCHB 2012 CZ eng C - Konferenční příspěvek (zahraniční konf.)
Pivoňková, Hana - Němcová, Kateřina - Horáková Brázdilová, Petra - Havran, Luděk - Macíčková-Cahová, Hana - Hocek, Michal - Fojta, Miroslav
Tail labelled oligonucleotide probes for the detection of DNA-protein interactions.
Chemistry of Nucleic Acid Components. 15th Symposium. Praha: Institute of Organic Chemistry and Biochemistry AS CR, v. v. i., 2011 - (Hocek, M.), s. 435-437. Collection Symposium Series, 12. ISBN 978-80-86241-37-1.
[Chemistry of Nucleic Acid Components /15./. Český Krumlov (CZ), 05.06.2011-10.06.2011]
Grant CEP: GA MŠMT LC512; GA MŠMT(CZ) LC06035; GA AV ČR(CZ) IAA400040901; GA AV ČR(CZ) IAA400040903; GA ČR(CZ) GAP301/11/2076
Výzkumný záměr: CEZ:AV0Z40550506; CEZ:AV0Z50040507; CEZ:AV0Z50040702
Klíčová slova: DNA * electrochemistry * tail labeling
Kód oboru RIV: CC - Organická chemie
DNA-protein interactions can be monitored via different ways. We introduce novel, fast and simple approaches in DNA-protein interaction detection based on electrochemical measurements of DNA alone (structure-sensitive DNA sensing), or DNA modified with osmium tetroxide bearing nitrogenous ligands, or measurements of redox-active moieties enzymatically attached to the end of a DNA substrate thus forming a labeled tail (by terminal transferase).
Trvalý link: http://hdl.handle.net/11104/0198898
Počet záznamů: 1