Počet záznamů: 1
Safety and efficacy of the immunosuppressive agent 6-tioguanine in murine model of acute and chronic colitis
- 1.0361620 - MBÚ 2012 RIV GB eng J - Článek v odborném periodiku
Kverka, Miloslav - Rossmann, Pavel - Tlaskalová-Hogenová, Helena - Klimešová, Klára - Jharap, B. - de Boer, N. - Vos, R. M. - van Bodegraven, A.A. - Lukáš, M. - Mulder, Ch.J.
Safety and efficacy of the immunosuppressive agent 6-tioguanine in murine model of acute and chronic colitis.
BMC Gastroenterology. Roč. 11, č. 1 (2011), s. 1-9. E-ISSN 1471-230X
Grant CEP: GA AV ČR KJB500200904; GA ČR GD310/08/H077; GA MŠMT 2B06155
Výzkumný záměr: CEZ:AV0Z50200510
Klíčová slova: INFLAMMATORY-BOWEL-DISEASE * NODULAR REGENERATIVE HYPERPLASIA * LOW-DOSE 6-THIOGUANINE
Kód oboru RIV: EC - Imunologie
Impakt faktor: 2.422, rok: 2011
Background: Oral thiopurines are effective and widely used in treatment of inflammatory bowel disease (IBD) in humans, although their use is limited due the development of adverse events. Here, we examine the efficacy and toxicity of oral treatment with 6-tioguanine (6-TG) and azathioprine (AZA) in a murine model of IBD
Trvalý link: http://hdl.handle.net/11104/0006519
Počet záznamů: 1