Počet záznamů: 1
Different effect of two synthetic coumarin-stilbene hybrid compounds on phagocyte activity
- 1.0356878 - BFÚ 2011 RIV SE eng J - Článek v odborném periodiku
Drábiková, K. - Perečko, T. - Nosál, R. - Račková, L. - Ambrožová, Gabriela - Lojek, Antonín - Šmidrkal, J. - Harmatha, Juraj - Jančinová, V.
Different effect of two synthetic coumarin-stilbene hybrid compounds on phagocyte activity.
Neuroendocrinology Letters. Roč. 31, č. 2 (2010), s. 73-78. ISSN 0172-780X. E-ISSN 2354-4716
Grant CEP: GA MŠMT(CZ) MEB0810013
Grant ostatní: GA ČR(CZ) GA203/07/1227
Program: GA
Výzkumný záměr: CEZ:AV0Z50040507; CEZ:AV0Z50040702; CEZ:AV0Z40550506
Klíčová slova: reactive species * phagocytosis * coumarin
Kód oboru RIV: BO - Biofyzika
Impakt faktor: 1.621, rok: 2010
Synthetic phenylcoumarin derivatives HHC (7-hydroxy-3-(4'-hydroxyphenyl) coumarin) and HHDC (7-hydroxy-3-(4'-hydroxyphenyl)-3,4-dihydrocoumarin) can affect ROS generation in human neutrophils and NO production by RAW 264.7 macrophages. The obtained results highlighted the different effects of HHC and HHDC on fagocyte functions, which might be due to their diverse free radical scavenging properties and lipophilicity features.
Trvalý link: http://hdl.handle.net/11104/0195286
Počet záznamů: 1