Cellular and mitochondrial respiration of Saccharomyces cerevisiae cells of different age

0354658 - MBÚ 2011 SK eng C - Konferenční příspěvek (zahraniční konf.)
Hlousková, J. - Volejníková, A. - Sigler, Karel - Pichová, Alena
Cellular and mitochondrial respiration of Saccharomyces cerevisiae cells of different age.
Annual Conference on Yeasts /37./. Smolenice: Springer, 2009, s. 92-92. ISSN 1336-4839.
[Annual Conference on Yeasts /37./. Smolenice (SK), 13.05.2009-15.05.2009]
Grant CEP: GA ČR GA301/07/0339; GA MŠMT 1M0570; GA MŠMT ME 938
Výzkumný záměr: CEZ:AV0Z50200510
Klíčová slova: Saccharomyces cerevisiae
Kód oboru RIV: EE - Mikrobiologie, virologie

Mitochondria are one of the causes of cell aging, because their production of oxygen radicals (ROS) and a decline of their function in the course of aging are causing defects in the respiratory machinery. We measured the respiration rate of whole cells and isolated mitochondria of different age groups, both chronological and replicative, of two yeast strains – wild type and isogenic RAS2val19 with the oncogenic mutation causing premature aging, and show the impact of oncogenic mutation on respiration rate in relation to the cell age
Trvalý link: http://hdl.handle.net/11104/0193615