Počet záznamů: 1
Program NovaQ
- 1.0350955 - MBÚ 2011 RIV CZ eng L4 - Software
Strohalm, Martin - Havlíček, Vladimír - Novák, Petr - Man, Petr - Pompach, Petr - Kavan, Daniel - Lemr, Karel
Program NovaQ.
Interní kód: FVZ/MBU/MS-Quantitation01 ; 2008
Technické parametry: Program pracuje na platformě Windows XP (Microsoft Corporation) a MacOS
Ekonomické parametry: Program poskytuje přesnější kvantitativní stanovení bílkovin
Grant CEP: GA MŠMT LC07017
Výzkumný záměr: CEZ:AV0Z50200510
Klíčová slova: NovaQ * protein * mass spectrometry
Kód oboru RIV: EE - Mikrobiologie, virologie
A new program NovaQ was developed for precise protein quantitation by mass spectrometry and SILAC labeling. The program works under Microsoft Wingows XP as well as MacOS patforms. By using peptide mass fingerprinting with 1.5 ppm mass tolerance we were able to utilize far more data retained in MS scans which would normally be missed by a standard processing method. This new way of data interpretation results in an improvement of the relevance of quantitation experiments and enabled us to search and quantify different types of post-translational modifications. Furthermore, we used this technique to distinguish among different protein isoforms, commonly returned by Mascot search engine
Trvalý link: http://hdl.handle.net/11104/0190812
Počet záznamů: 1