Počet záznamů: 1
Sustained deficiency of mitochondrial complex I activity during long periods of survival after seizures induced in immature rats by homocysteic acid
- 1.0341983 - FGÚ 2011 RIV GB eng J - Článek v odborném periodiku
Folbergrová, Jaroslava - Ješina, Pavel - Haugvicová, Renata - Lisý, Václav - Houštěk, Josef
Sustained deficiency of mitochondrial complex I activity during long periods of survival after seizures induced in immature rats by homocysteic acid.
Neurochemistry International. Roč. 56, č. 3 (2010), s. 394-403. ISSN 0197-0186. E-ISSN 1872-9754
Grant CEP: GA ČR(CZ) GA309/05/2015; GA ČR GA309/08/0292; GA MŠMT(CZ) 1M0520
Výzkumný záměr: CEZ:AV0Z50110509
Klíčová slova: homocysteic acid-induced seizures * mitochondrial complex I activity * persisting decrease
Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
Impakt faktor: 3.601, rok: 2010
A marked decrease (cca60 %) of mitochondrial complex I activity (observed during the acute phase of seizures induced in immature rats by homocysteic acid) persists during long periods of survival (up to 5 weeks) following seizures. It is accompanied by significant increase of three mitochondrial markers of oxidative damage. The decrease of complex I activity was substantially reduced by treatment with selected free radical scavengers
Trvalý link: http://hdl.handle.net/11104/0184816
Počet záznamů: 1