Monoclonal antibodies to human seminal plasma proteins

0341144 - BTÚ 2010 RIV IT eng A - Abstrakt
Čapková, Jana - Margaryan, Hasmik - Elzeinová, Fatima - Koubek, Pavel - Pěknicová, Jana
Monoclonal antibodies to human seminal plasma proteins.
Proceeding. Monduzzi, 2009. s. 1-7. ISBN 978-88-7587-530-5.
[9th International Congress of Andrology. 07.03.2009-10.03.2009, Barcelona]
Grant CEP: GA MŠMT(CZ) 1M06011; GA MŠMT(CZ) 2B06151
Výzkumný záměr: CEZ:AV0Z50520701
Klíčová slova: monoclonal antibody * human seminal plasma * sperm proteins * MALDI TOF * 2D-electrophoresis
Kód oboru RIV: EC - Imunologie

Seven monoclonal antibodies – Hs-3, Hs-9, Hs-16, Hs-23, Hs-31, Hs-32, Hs-37 – to human seminal plasma proteins were established. These antibodies recognized apolipoprotein J (clusterin), semenogelin I, secretory actin-binding protein (SABP) and enolase I. Using the Hs-16 antibody increased expression of SABP was revealed in men with pathological spermiograms suggesting an association with fertility failure.
Trvalý link: http://hdl.handle.net/11104/0184221