NMR study of cisImage trans isomerism in N-methylated lactams with 11- and 13-membered rings

0331257 - ÚMCH 2010 NL eng J - Článek v odborném periodiku
Lövy, Jan - Dybal, Jiří - Puffr, Rudolf - Doskočilová, Danica
NMR study of cisImage trans isomerism in N-methylated lactams with 11- and 13-membered rings.
Journal of Molecular Structure. Roč. 66, - (1980), s. 301-308. ISSN 0022-2860. E-ISSN 1872-8014
Klíčová slova: cis—trans isomerism
Kód oboru RIV: CD - Makromolekulární chemie

From 1H-NMR spectra of 1-methyl-azacyclo-undeca-2-one and 1-methyl-azacyclo-trideca-2-one, the bands corresponding to the cis and trans forms have been assigned and analyzed; based on this analysis, conformational structures about the C-C bond next to nitrogen are proposed. By analysis of the relative areas and shapes of the N-methyl bands measured for the two lactams in 1,1,2,2-tetrachloroethane-d2, over a broad temperature range, the equilibrium and thermodynamic parameters characterizing the cis—trans isomerism of the amide bond in these lactams have been determined. Peaks corresponding to the cis and trans forms in the 13C-NMR spectra of these lactams have also been assigned.
Trvalý link: http://hdl.handle.net/11104/0005507